While baking soda is the leavning agent used by Donia, we are sad to say that Baking Soda alone is not enough to invoke the chemical reaction as described in Insignia - A Venmous Intervention.

You do not have an adequeate source of spider venom to complete the ingredients. However, here are plenty of other great things you can use your Sodium Bicarbonate for:

Baking soda is sodium bicarbonate (NaHCO₃). A mild alkali that releases carbon dioxide gas when it meets acid or heat, acts as a mild abrasive, buffers pH, and can neutralize some odors. The FDA treats food-grade baking soda as generally recognized as safe for use as a food additive, occasional antacid, and toothpaste ingredient.

Below is a broad compilation of documented uses, grouped by how well they hold up. “Good” here means commonly effective or officially used when applied correctly and in limited amounts. “Bad or overhyped” means the chemistry does not deliver what people expect, evidence is weak or absent, or the risks are high. Food and cooking (strong uses)

Kitchen & Cooking

• Leavening agent in cakes, quick breads, cookies, muffins, and soda bread when combined with an acid (buttermilk, yogurt, lemon juice, vinegar, cream of tartar, or cocoa). Heat also decomposes it and releases CO₂. Without enough acid it leaves a soapy or bitter taste and can yellow baked goods.
• Component of baking powder (already mixed with a dry acid).
• Meat tenderizer, especially in some Chinese cooking methods.
• Making omelets or scrambled eggs slightly fluffier (small amount).
• pH control and acidity regulator in processed foods and some beverages (E500).
• Helping retain green color in certain cooked vegetables.
• Soaking produce to reduce some surface pesticide residues (supported for certain fruits such as apples; does not remove pesticides that have already penetrated).
• Animal-feed additive to help buffer rumen pH and aid digestion.

Deodorizer & Cleanser

Household cleaning and deodorizing (generally good when used as a mild abrasive or odor absorber)

• Scrubbing sinks, counters, ovens, tubs, tiles, and scorched pans (paste with a little water). Mild abrasive that is gentler than many commercial scouring powders.
• Boosting laundry detergent, helping lift some stains, and softening water.
• Absorbing odors in refrigerators, trash cans, carpets, shoes, and dishwashers (open box or sprinkle). It does not “eat” odors so much as it can neutralize some acidic or basic odor molecules.
• Cleaning plastic food-storage containers of stains.
• Polishing silver (with aluminum foil and hot water).
• Removing surface rust in some cases.
• Soda blasting (industrial-scale version) for gentle surface cleaning.
• Light drain freshening (odor control). It is not a reliable clog remover—see the “overhyped” section.

Disinfectants

It is only a weak disinfectant or fungicide, so it is not a substitute for proper sanitizers on high-risk surfaces.

• Ingredient in many toothpastes: mild abrasive that helps remove surface stains and plaque; raises oral pH and can reduce some bacteria. Baking soda toothpastes that also contain fluoride are the better option. Plain baking soda has low abrasivity (RDA well below safety limits) but contains no fluoride, so it should not replace regular fluoride toothpaste. Use it occasionally (a few times a week at most), with a soft brush and light pressure. Do not mix it with lemon juice or vinegar—the acid damages enamel.
• Homemade mouthwash (½ teaspoon in water) for temporary breath freshening.
• Underarm or foot deodorant (powder or in commercial sticks). Neutralizes odor rather than blocking sweat.
• Paste or bath soak for minor insect bites, stings, poison ivy, and some itchy rashes. Many over-the-counter products already contain it for this purpose.
• Occasional gentle exfoliant or hair-buildup remover. Daily or facial use is riskier (see below).

Medical and Pharmaceutical

(official or evidence-supported, usually not DIY)

• Occasional antacid for heartburn or indigestion (½ teaspoon fully dissolved in at least ½ cup water). FDA-approved for short-term use. Do not use for more than two weeks without medical advice, and never on a very full stomach or after heavy drinking—the sudden CO₂ can theoretically contribute to gastric rupture in rare cases.
• Intravenous treatment (hospital only) for certain cases of metabolic acidosis, some drug overdoses (e.g., tricyclic antidepressants, salicylates), hyperkalemia in acidosis, and urine alkalinization.
• Prescribed oral tablets for some patients with chronic kidney disease to treat metabolic acidosis.
• Component of some effervescent tablets and mouthwash products.
• Topical paste or soak for minor skin irritation from bites or poison ivy.
• Possible modest benefit for short-duration, high-intensity athletic performance (“soda loading,” typically ~0.3 g per kg body weight 60–180 minutes beforehand). Evidence is mixed; gastrointestinal side effects are common. Not recommended without professional guidance.
• Weak supporting evidence that raising tumor pH might help some chemotherapy agents work better in certain experimental settings; this is not a home cancer treatment.

Industrial, agricultural, and specialty uses

• Dry-chemical fire extinguishers (releases CO₂ and water vapor when heated; useful on some grease and electrical fires, not deep-fat fryers).
• Flue-gas treatment to capture sulfur dioxide.
• Wastewater pH adjustment and odor control.
• Leather tanning, paper sizing, textile dyeing (pH control), plastics (blowing agent for foams), glass and ceramics.
• Agricultural foliar spray to suppress some fungal growth (powdery mildew); overuse can damage plants.
• “Black snake” fireworks (thermal decomposition produces the ash snake).
• Laboratory buffering and acid neutralization.

mportant safety notes that apply across uses

• 1 teaspoon of baking soda ≈ 1,259 mg sodium.
• Never swallow large amounts of dry powder.
• Keep the box away from children; ingestion of a large quantity can cause serious toxicity (alkalosis, electrolyte chaos, gastric distension).
• People on sodium-restricted diets, with hypertension, heart failure, kidney disease, or who are pregnant should avoid ingesting it unless a doctor specifically recommends a pharmaceutical product.
• Do not take it within 1–2 hours of other oral medications; it changes stomach pH and can alter absorption.

Overhyped, ineffective, or risky uses

• Baking soda + vinegar as a drain clog remover. The fizz is mostly theater. The reaction quickly produces water, carbon dioxide, and sodium acetate (a weak salt solution). In an open drain there is little pressure and almost no dissolving power against grease, hair, or soap scum. Any improvement usually comes from the hot water flush that follows. It can be used for light odor control but is a poor unclogger.
• Daily or long-term drinking of baking-soda water for “detox,” weight loss, alkalizing the body, or general health. There is no good evidence for most of these claims. One teaspoon contains roughly 1,200 mg of sodium—close to or above many people’s entire daily limit. Risks include metabolic alkalosis, electrolyte imbalance (low potassium), high blood pressure, fluid retention, stomach rupture, and dangerous interactions with medications. Especially unsafe for children, pregnant people, and anyone with heart, kidney, or blood-pressure problems.
• Replacing fluoride toothpaste entirely or using baking soda daily with a hard brush. Enamel wear and lack of cavity protection become issues over time.
• Regular facial masks, acne treatment, or “brightening” scrubs. Skin’s natural pH is acidic (about 4.5–5.5). Baking soda is alkaline (~8–9) and can disrupt the barrier, causing dryness, irritation, more breakouts, or even darkening in some skin tones. Occasional body-bath use for itching is different from daily face use.
• Cancer cure or “alkalize to starve cancer.” Unproven and warned against by major cancer organizations.
• Reliable household disinfectant. It has only weak antimicrobial activity.
• Weed killer in garden beds (high sodium harms soil and desirable plants).
• Mixing with lemon or vinegar on teeth.
• Mixing with Spider Venom after depleating a victims cardiovascular system of fluids to dissaperate into thin air.

I

The largest practical lists come from combining official medical indications, industrial applications, well-tested household tricks, and the many folk uses that either work modestly or fail for clear chemical reasons. Food-grade baking soda is cheap and useful when you treat it as a mild alkali and abrasive rather than a miracle powder. For anything beyond cooking, cleaning, or occasional antacid use, check with a professional first